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Kraft

Prof. Dr.
Claudine Kraft

Institute of Biochemistry and Molecular Biology
Department of Biochemistry II
Phone: 0049-761/203-5221

www.biochemie.uni-freiburg.de/ag/kraft

 

CV

  • 2000-2001 Diploma thesis, University of Manchester, UK; Lab of Steve High
  • 2002-2005 PhD thesis, IMP Vienna, Austria; Lab of Jan-Michael Peters
  • 2006-2011 Postdoc, ETH Zürich, Switzerland; Lab of Matthias Peter
  • 2011-2017 Group leader, MFPL University of Vienna, Austria
  • Seit 2017 Professor (W3), University of Freiburg, Germany

Focus of research

  • Molecular mechanisms in autophagy from yeast to mammals

Selected publications

  • Torggler R, Papinski D, Brach T, Bas L, Schuschnig M., Pfaffenwimmer T., Rohringer S, Matzhold T, Schweida D, Brezovich A and Kraft C (2016). Two Independent Pathways within Selective Autophagy Converge to Activate Atg1 Kinase at the Vacuole. Molecular Cell 64: 221-235. DOI:10.1016/j.molcel.2016.09.008
  • Papinski D, Schuschnig M, Reiter W, Wilhelm L, Barnes C, Majolica A, Hansmann I, Pfaffenwimmer T, Kijanska M, Stoffel I, Lee SS, Brezovich A, Lou HJ, Turk BE, Aebersold R, Ammerer G, Peter M and Kraft C (2014) Early steps in autophagy depend on direct phosphorylation of Atg9 by the Atg1 kinase. Molecular Cell 53: 471–483. DOI: 10.1016/j.molcel.2013.12.011
  • Pfaffenwimmer T, Reiter W, Brach T, Nogellova V, Papinski D, Schuschnig M, Abert C, Ammerer G, Martens S and Kraft C (2014) The Hrr25 kinase promotes selective autophagy by phosphorylating the cargo-receptor Atg19. EMBO Reports 15: 862-870. DOI: 10.15252/embr.201438932
  • Kraft C*, Kijanska M, Kalie E, Siergiejuk E, Lee S, Semplicio G, Stoffel I, Brezovich A, Verma M, Hansmann I, Ammerer G, Hofmann K, Tooze S, Peter M* (2012) Binding of the Atg1/ULK1 kinase to the ubiquitin-like protein Atg8 regulates autophagy. The EMBO journal 31: 3691-703 (* corresponding authors). DOI: 10.1038/emboj.2012.225
  • Kraft C*, Deplazes A, Sohrmann M, Peter M* (2008) Mature ribosomes are selectively degraded upon starvation by an autophagy pathway requiring the Ubp3p/Bre5p ubiquitin protease. Nature Cell Biol 10: 602-610 (* corresponding authors). DOI: 10.1038/ncb1723