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Meyer-Luehmann

Prof. Dr.
Melanie Meyer-Luehmann

Department of Neurology and Neuroscience
Phone: 0049-761-270-52350

www.uniklinik-freiburg.de/?id=9025

CV

  • 1993-1999 Graduate studies of Biology, University of Freiburg
  • 2000-2004 PhD thesis, University of Basel, Switzerland
  • 2004-2008 Postdoctoral fellow at the Hertie Institute of Clinical Brain Research, Tübingen and Harvard Medical School, Boston, USA
  • 2008-2011 Independent group leader at the Adolf-Butenandt-Institut, Ludwig-Maximilians-University Munich
  • Seit 2011 Full Professor of functional restoration in the CNS, Department of Neurology and Neuroscience (W3), Medical Center – University of Freiburg

Focus of research

  • Neurodegenerative Diseases
  • Plaque development
  • Neurodegeneration

Selected publications

  • Bachhuber T, Katzmarski N, McCarter JF, Loreth D, Tahirovic S, Kamp F, Abou-Ajram C, Nuscher B, Serrano-Pozo A, Müller A, Prinz M, Steiner H, Hyman BT, Haass C, Meyer-Luehmann M. Inhibition of amyloid-beta plaque formation by alpha-synuclein. Nat Med. 2015; 21(7):802-7.
  • Meyer-Luehmann M, Spires-Jones TL, Prada C,Garcia-Alloza M, de Calignon A, Rozkalne A, Koenigsknecht-Talboo J, Holtzman DM, Bacskai BJ, Hyman BT. Rapid appearance and local toxicity of amyloid-beta plaques in a mouse model of Alzheimer's disease. Nature. 2008; 451(7179):720-4.
  • Meyer-Luehmann M, Coomaraswamy J, Bolmont T, Kaeser S, Schaefer C, Kilger E, Neuenschwander A, Abramowski D, Frey P, Jaton AL, Vigouret JM, Paganetti P, Walsh DM, Mathews PM, Ghiso J, Staufenbiel M, Walker LC, Jucker M. Exogenous induction of cerebral beta-amyloidogenesis is governed by agent and host. Science. 2006; 313(5794):1781-4.
  • Meyer-Luehmann M, Stalder M, Herzig MC, Kaeser SA, Kohler E, Pfeifer M, Boncristiano S, Mathews PM, Mercken M, Abramowski D, Staufenbiel M, Jucker M. Extracellular amyloid formation and associated pathology in neural grafts. Nat Neurosci. 2003; 6(4):370-7.

Research methods

  • Intracerebral injections
  • Two-photon microscopy