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Peters

Prof. Dr.
Christoph Peters

Institute of Molecular Medicine and Cell Research
Head of Institute
Phone: 0049-761-203-9600-9601

www.mol-med.uni-freiburg.de

CV

  • 1975-1983 Medical School, University of Münster and University of California, San Diego
  • 1984-1996 Postdoc and Junior Group Leader, Center of Molecular Biology Heidelberg, Center of Biochemistry and Cell Biology, University of Göttingen
  • 1996-1999 Associate professor of Medical Molecular Biology (C3), Department Hematology/Oncology, Medical Center - University of Freiburg
  • Since 1999 Full Professor of Molecular Medicine (C4) and Director of the Institute of Molecluar Medicine and Cell Research, University of Freiburg
  • Since 2001 Coordinator BSc and MSc Molecular Medicine
  • 2005-2010 Dean of the Faculty of Medicine, University of Freiburg
  • Since 2010 Coordinator of the Collaborative Research Center 850 "Control of Cell Motility in Morphogenesis, Cancer Invasion and Metastasis" (SFB 850)
  • Since 2011 Dean of Studies Molecular Medicine
  • Since 2012 Scientific Director of the Comprehensive Cancer Center Freiburg (CCCF)
  • Since 2012 Coordinator of the partner site Freiburg of the German Cancer Consortium

Focus of research

  • In vivo functions of proteolytic enzymes
  • Tumor invasion and metastasis
  • Tumormicroenvironment and intercellular communication

Selected publications

  • Sevenich L, Schurigt U, Sachse K, Gajda M, Werner F, Müller S, Vasiljeva O, Schwinde A, Klemm N, Deussing J, Peters C, Reinheckel T. Synergistic antitumor effects of combined cathepsin B and cathepsin Z defi ciencies on breast cancer progression and metastasis in mice. Proc Natl Acad Sci U S A. 2010; 107(6):2497-2502.
  • Vasiljeva O, Papazoglou A, Kruger A, Brodoefel H, Korovin M, Deussing J, Augustin N, Nielsen BS, Almholt K, Bogyo M, Peters C, Reinheckel T. Tumor cell-derived and macrophage-derived cathepsin B promotes progression and lung metastasis of mammary cancer. Cancer Res. 2006; 66(10):5242-5250.
  • Nakagawa T, Roth W, Wong P, Nelson A, Farr A, Deussing J, Villadangos JA, Ploegh H, Peters C, Rudensky AY. Cathepsin L: critical role in Ii degradation and CD4 T cell selection in the thymus. Science. 1998;280(5362):450-3.
  • Eberle W, Sander C, Klaus W, Schmidt B, von Figura K, Peters C. The essential tyrosine of the internalization signal in lysosomal acid phosphatase is part of a beta turn. Cell. 1991; 67(6):1203-9.

Research methods

  • Genetically engineered mouse models
  • Proteomics
  • Bioinformatics and Systems Medicine