You are here: Home Faculty Professors Reinheckel

Reinheckel

Prof. Dr.
Thomas Reinheckel

Institute of Molecular Medicine and Cell Research
Phone: 0049-761-203-9606
thomas.reinheckel@mol-med.uni-freiburg.de

CV

  • 1989-1996 Studies of Medicine, University of Magdeburg
  • 1993-1994 Dept. Biochemistry and Molecular Biology; Albany Medical College, Albany N.Y
  • 1996-1997 Internship / Residency, Dept. of General Surgery, University Hospital Magdeburg
  • 2002-2012 Group leader; Institute of Molecular Medicine and Cell Research, University of Freiburg
  • Since 2013 Full Professor (W3), Institute of Molecular Medicine and Cell Research, University of Freiburg

Focus of research

  • Protease Functions in Health and Disease
  • Initiation, Progression and Metastasis of Solid Cancers

Selected publications

  • Ketterer S, Gomez-Auli A, Hillebrand LE, Petrera A, Ketscher A, Reinheckel T. Inherited diseases caused by mutations in cathepsin protease genes. FEBS J. 2016; Dec 7. doi: 10.1111/febs.13980.
  • Tholen M, Hillebrand LE, Tholen S, Sedelmeier O, Arnold SJ, Reinheckel T. Out-of-frame start codons prevent translation of truncated nucleo-cytosolic cathepsin L in vivo. Nat Commun. 2014; 5, 4931-4941.
  • Sevenich L, Schurigt U, Sachse K, Gajda M, Werner F, Muller S, Vasiljeva O, Schwinde A, Klemm N, Deussing J, Peters C, and Reinheckel T. Synergistic antitumor effects of combined cathepsin B and cathepsin Z defi ciencies on breast cancer progression and metastasis in mice. Proc Natl Acad Sci U S A. 2010; 107, 2497-2502.
  • Reiser J, Adair B, and Reinheckel T. Specialized roles for cysteine cathepsins in health and disease. J Clin Invest. 2010; 120, 3421-3431.
  • Stypmann J, Glaser K, Roth W, Tobin DJ, Petermann I, Matthias R, Mönnig G, Haverkamp W, Breithardt G, Schmahl W, Peters C, and Reinheckel T. Dilated cardiomyopathy in mice deficient for the lysosomal cysteine peptidase cathepsin L. Proc Natl Acad Sci U S A. 2002; 99, 6234-6239.