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Stäheli

Prof. Dr.
Peter Stäheli

Institute of Virology
Phone: 0049-761-203-6579

www.uniklinik-freiburg.de/virologie-en

CV

  • 1978-1981 PhD thesis Microbiology, ETH Zürich
  • 1981-1985 Postdoc Virology, University of Zürich
  • 1985-1987 Postdoc Scripps Research Institute, La Jolla, CA
  • 1987-1990 Junior Group Leader Virology, University of Zürich
  • Since 1990 Professor of Virology (C3), Medical Center - University of Freiburg

Focus of research

  • Influenza viruses and other respiratory RNA viruses
  • Antiviral host defense systems: interferons and other antiviral cytokines

Selected publications

  • Deeg CM, Hassan E, Mutz P, Rheinemann L, Götz V, Magar L, Schilling M, Kallfass C, Nürnberger C, Soubies S, Kochs G, Haller O, Schwemmle M, Staeheli P. In vivo evasion of MxA by avian infl uenza viruses requires human signature in the viral nucleoprotein. J Exp Med. 2017; 214(5):1239-1248.
  • Hernández PP, Mahlakõiv T, Yang I, Schwierzeck V, Nguyen N, Guendel F, Gronke K, Ryffel B, Hölscher C, Dumoutier L, Renauld JC, Suerbaum S, Staeheli P, Diefenbach A. Interferon-λ and interleukin 22 act synergistically for the induction of interferon-stimulated genes and control of rotavirus infection. Nat Immunol. 2015; 16(7):698-707.
  • Mahlakõiv T, Hernandez P, Gronke K, Diefenbach A, Staeheli P. Leukocyte-derived IFN-α/β and epithelial IFN-λ constitute a compartmentalized mucosal defense system that restricts enteric virus infections. PLoS Pathog. 2015; 11(4):e1004782.
  • Pott J, Mahlakõiv T, Mordstein M, Duerr CU, Michiels T, Stockinger S, Staeheli P, Hornef MW. IFN-lambda determines the intestinal epithelial antiviral host defense. Proc Natl Acad Sci USA. 2011; 108(19):7944-9.
  • Mordstein M, Kochs G, Dumoutier L, Renauld JC, Paludan SR, Klucher K, Staeheli P. Interferon-lambda contributes to innate immunity of mice against infl uenza A virus but not against hepatotropic viruses. PLoS Pathog. 2008; 4(9):e1000151.

Research methods

  • Animal facility for infection experiments with viruses of biosafety levels 2 and 3