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Prof. Dr.
Hanspeter Pircher

Institute for Immunology
Phone 0049-761-203-6521


  • 1981-1985 PhD Thesis; ETH/University Hospital Zurich
  • 1986-1987 Post-Doc, Ontario Cancer Institute, Toronto
  • 1988-95 Research Fellow, Institute of Exp. Immunology, University of Zurich
  • Since 1995 Professor (C3) and Director of the Institute for Immunology, Medical Center – University of Freiburg

Focus of research

  • Tissue-resident memory T cells: lymphocytes with fascinating features
  • Role of B cells and NK cells in the immune response against lymphocytic choriomeningitis virus (LCMV)

Selected publications

  • Woyciechowski S, Hofmann M, Pircher H. alpha4 beta1 integrin promotes accumulation of tissue-resident memory CD8+ T cells in salivary glands. Eur J Immunol. 2017; 47(2):244-250.
  • Schwartzkopff S, Woyciechowski S, Aichele U, Flecken T, Zhang N, Thimme R, Pircher H. TGF-beta downregulates KLRG1 expression in mouse and human CD8(+) T cells. Eur J Immunol. 2015; 45(8):2212-7.
  • Straub T, Schweier O, Bruns M, Nimmerjahn F, Waisman A, Pircher H. Nucleoprotein-specific nonneutralizing antibodies speed up LCMV elimination independently of complement and FcgammaR. Eur J Immunol. 2013; 43(9):2338-48.
  • Mueller K, von Mässenhausen A, Aichele U, Stärck L, Leisegang M, Uckert W, Pircher H. Protective capacity of virus-specific T cell receptor-transduced CD8 T cells in vivo. J Virol. 2012; 86(19):10866-9.
  • Hofmann M, Pircher H. E-cadherin promotes accumulation of a unique memory CD8 T-cell population in murine salivary glands. Proc Natl Acad Sci USA. 2011; 108(40):16741-6.

Research methods

  • Viral infection models