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Prof. Dr.
Annette Hildegard Schmitt-Gräff

Institute of Surgical Pathology
Phone: 0049-761 2708060


  • 1986 Habilitation in Anatomical Pathology, University of Düsseldorf, supported by a DFG scholarship (Department of Experimental Pathology, Prof. G. Gabbiani, Universityhospital Geneva) 
  • 1990-1992 Leading Consultant at the Institute for Clinical Pathology, Department of Pathology, Universityhospital  Geneva, Switzerland
  • 1992 Extraordinary Professor
  • 1992-1995 Consultant at the Institute of Pathology, Freie Universität Berlin (Chairman: Prof. Dr. Harald Stein)
  • Since 1995 Professor (C3) of Pathology, University of Freiburg
  • 2009-2011 President of the International Academy of Pathology (IAP), German Division
  • Since 2016 member of the International Education Committee of the IAP Central

Focus of research

  • Pathology of hemato-lymphoid neoplasms including disease manifestations in lymph nodes, bone marrow, extranodal sites with special interest in the hematopoietic niche
  • Liver and gastrointestinal pathology with focus on neuroendocrine neoplasms and tumors of the hepatobiliary tree
  • Graft-versus-Host disease after allogeneic hematopoietic cell transplantation

Selected publications

  • Schmitt-Graeff AH, Nitschke R, Zeiser R.The Hematopoietic Niche in Myeloproliferative Neoplasms. Mediators Infl amm. 2015; 2015:347270.
  • Schmitt-Graeff AH, Erben P, Schwaab J, Vollmer-Kary B, Metzgeroth G, Sotlar K, Horny HP, Kreipe HH, Fisch P, Reiter A. The FIP1L1-PDGFRA fusion gene and the KIT D816V mutation are coexisting in a small subset of myeloid/lymphoid neoplasms with eosinophilia. Blood. 2014; 123:595-7.
  • Schmitt-Graeff AH, Duerkop H, Vollmer-Kary B, Haxelmans S, Nitschke R, Fisch P, Germing U, Stein H.Clonal relationship between langerhans cell histiocytosis and myeloid sarcoma. Leukemia. 2012; 26:1707-10.
  • Schmitt-Graeff AH, Teo SS, Olschewski M, Schaub F, Haxelmans S, Kirn A, Reinecke P, Germing U, Skoda RC. JAK2V617F mutation status identifies subtypes of refractory anemia with ringed sideroblasts associated with marked thrombocytosis. Haematologica. 2008; 93:34-40.
  • Schmitt-Gräff A, Ertelt V, Allgaier HP, Koelble K, Olschewski M, Nitschke R, Bochaton-Piallat ML, Gabbiani G, Blum HE. Cellular retinol-binding protein-1 in hepatocellular carcinoma correlates with beta-catenin, Ki-67 index, and patient survival. Hepatology. 2003; 38:470-80.