Gekara

Center of Microbiology and Hygiene
Institute of Microbiology and Hygiene
Phone: 0049-761-203-6521
nelson.ongondo.gekara@uniklinik-freiburg.de
www.uniklinik-freiburg.de/mikrobiologie-en

2002-2005 Ph.D studies and Postdoc, Helmholtz Center for Infection Research (HZI) and Technical University Braunschweig
2006-2010 Postdoc, Helmholtz Center for Infection Research (HZI) and University of Cologne
2010-2019 Assistant Professor, Molecular Infection Medicine Sweden (MIMS), Umea University, Sweden
2019-2022 Associate Professor, Department of Molecular Biosciences, Wenner Gren Institute, Stockholm Univesity, Sweden
Since 2022 Full Professor of Microbiology and Molecular Infections Immunology, Institute for Medical Microbiology and Hygiene, Medical Center - University of Freiburg

Erttmann SF, Swacha P, Aung KM, Brindefalk B, Jiang H, Härtlova A, Uhlin BE, Wai SN and Gekara NO. The gut microbiota prime systemic antiviral immunity via the cGAS-STING-IFN-I axis. Immunity. 2022 May 10;55(5):847-861)
Jiang H, Xue H, Panda S, Kawale A, Hooy, R M, Liang F, Sohn J, Sung P & Gekara NO. Chromatin-bound cGAS is an inhibitor of DNA repair and accelerates genome destabilization and cell death. EMBO Journal. 2019 Sep 23:e102718
Erttmann SF, Hartlova A, Sloniecka M, Hosseinzadeh A, Rofougaran R, Edgren T, Raffi1 F.A.M, Resch U, Fällman M, Ek T, and Gekara N.O. Loss of the DNA damage repair kinase ATM impairs inflammasome dependent anti-bacterial innate immunity via oxidative stress. Immunity. 2016. Jul 19;45(1):106-18)
Panda S, Nilsson J.A and Gekara N.O. Deubiquitinase MYSM1 Regulates Innate Immunity through Inactivation of TRAF3 and TRAF6 Complexes. Immunity. 2015 Oct 20;43(4):647-59
Hartlova A, Erttmann S.F, Raffi F.A.M., Schmalz A. M., Resch U, Anugula S, Lienenklaus S, Nilsson L.M., Kröger A, Nilsson J.A., Ek T, Weiss S and Gekara N.O. DNA Damage Primes the Type I Interferon System via the Cytosolic DNA Sensor STING to Promote Anti-Microbial Innate Immunity. Immunity. 2015 Feb 17;42(2):332-43