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Eyerich

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Prof. Dr.
Kilian Eyerich

Department of Dermatology
Medical Director
Phone: 0049-761-27067160

www.uniklinik-freiburg.de/hautklinik

CV

  • 2014-2019 Heisenberg Professor for Experimental Dermato-immunology, Technical University of Munich
  • 2019-2021 Professor and Chair for Dermatology and Venerology, Karolinska Institutet, Stockholm
  • Since 11/2021 Guest Professor, Karolinska Institutet, Stockholm
  • Since 2021 Full Professor and Medical Director, Department of Dermatology, Medical Center – University of Freiburg

Focus of research

  • To re-classify the disease ontology of inflammatory and autoimmune skin diseases based on molecular endotypes
  • Interaction of adaptive immune cells and resident epithelial cells during chronic inflammation
  • Moelcular diagnostics of inflammatory skin diseases and cancer

Selected publications

  • Batra R, Garzorz-Stark N, Lauffer F, Jargosch M, Pilz AC, Roenneberg S, Schäbitz A, Böhner A, Seiringer P, Thomas J, Fereydouni B, Kutkaite G, Menden M, Tsoi LC, Gudjonsson JE, Theis JF, Biedermann T, Schmidt-Weber CB, Müller NS, Eyerich S, Eyerich K. Integration of phenomics and transcriptomics data to reveal drivers of inflammatory processes of the skin. bioRxiv. 2020.07.25.221309.
  • Lauffer F, Jargosch M, Krause L, Garzorz-Stark N, Franz R, Roenneberg S, Böhner A, Mueller NS, Theis FJ, Schmidt-Weber CB, Biedermann T, Eyerich S, Eyerich K. Type I immune response induces keratinocyte necroptosis and is associated with interface dermatitis. J Invest Dermatol. 2018; 138(8):1785-1794.
  • Garzorz-Stark N, Lauffer F, Krause L, Thomas J, Atenhan A, Franz R, Roenneberg S, Boehner A, Jargosch M, Batra R, Mueller NS, Haak S, Groß C, Groß O, Traidl-Hoffmann C, Theis FJ, Schmidt-Weber CB, Biedermann T, Eyerich S, Eyerich K. Toll-like receptor 7/8 agponists stimulate plasmacytoid dendritic cells to initiate Th17-deviated acute contact dermatitis in human subjects. J Allergy Clin Immunol. 2018; 141(4):1320-1333.
  • Quaranta M, Knapp B, Garzorz N, Mattii M, Pullabhatla V, Pennino D, Andres C, Traidl-Hoffmann C, Cavani A, Theis FJ, Ring J, Schmidt-Weber CB, Eyerich S, Eyerich K. Intraindividual genome expression analysis reveals a specific molecular signature of psoriasis and eczema. Sci Transl Med. 2014; 6(244):244ra90.
  • Eyerich S, Onken AT, Weidinger S, Franke A, Nasorri F, Pennino D, Grosber M, Pfab F, Schmidt-Weber CB, Mempel M, Hein R, Ring J, Cavani A, Eyerich K. Mutual antagonism of T cells causing psoriasis and atopic eczema. N Engl J Med. 211; 365(3):231-8.

Research methods

  • Spatial transcriptomics from skin lesions
  • Image-based machine learning (Canfield Vectra 360WB system)
  • Human cell culture models of chronic inflammatory skin diseases