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Häcker

Haecker

Prof. Dr.
Georg Häcker

Center of Microbiology and Hygiene
Institute of Microbiology and Hygiene
Medical Director
Phone: 0049-761-203-6532

www.uniklinik-freiburg.de/mikrobiologie-en

CV

  • 1993-1995 DFG Training Fellowship at the Walter and Eliza Hall Institute of Medical Research (WEHI), Melbourne
  • 1996-2009 Doctor/Scientist (group leader) and Consultant, Institute of Medical Microbiology, TU Munich
  • 1998-2000 Lecturer, Institute of Medical Microbiology, TU Munich
  • 2000-2009 Professor (C3), Institute of Medical Microbiology, Immunology and Hygiene, TU Munich, Germany
  • Since 2009 Full professor (W3) and Medical Director, Institute of Microbiology and Hygiene, Medical Center - University of Freiburg, Germany

Focus of research

  • Molecular mechanisms of cell death
  • Cell death in the immune system, inflammation
  • Infectious biology of Chlamydia trachomatis

Selected publications

  • Weber A, Heinlein M, Dengjel J, Alber C, Singh PK, Häcker G. The deubiquitinase Usp27x stabilizes the BH3-only protein Bim and enhances apoptosis. EMBO Rep. 2016; 17(5):724-38.
  • Schwab L, Goroncy L, …, Hildebrandt GC*, Häcker G*, Zeiser R*. Neutrophil granulocytes recruited upon translocation of intestinal bacteria enhance graft-versus-host disease via tissue damage. Nat Med. 2014; 20(6): 648-54. *Equal contribution.
  • Gentle IE, Moelter I, Lechler N, Bambach S, Vucikuja S, Häcker G*, Aichele P*. Inhibitors of apoptosis proteins (IAPs) are required for effective T-cell expansion/survival during antiviral immunity in mice. Blood. 2014; 123(5):659-68. *Equal contribution.
  • Feoktistova M, Geserick P, Kellert B, Dimitrova DP, Langlais C, Hupe M, Cain K, MacFarlane M, Häcker G, Leverkus M. cIAPs block Ripoptosome formation, a RIP1/caspase-8 containing intracellular cell death complex differentially regulated by cFLIP isoforms. Mol Cell. 2011; 43(3):449-63.
  • Paschen SA, Christian JG, Vier J, Schmidt F, Walch A, Ojcius DM, Häcker G. Cytopathicity of Chlamydia is largely reproduced by expression of a single chlamydial protease. J Cell Biol. 2008; 182(1):117-27.