Hengel

Prof. Dr.
Hartmut Hengel
Institute of VirologyMedical Director
Phone: 0049-761-203-6534
hartmut.hengel@uniklinik-freiburg.de
www.uniklinik-freiburg.de/virologie-en
CV
- 1989 MD, University of Ulm (Prof. Dr. Hermann Wagner, PhD, Institute of Microbiology, Department of Immunology)
- 1998 Habilitation in Virology, Venia legendi; Ludwig-Maximilians-Universität Munich
- 2002 Appointment as Director and Professor at Robert Koch-Institute, Berlin
- 2004-2012 Full professor and founding Director, Institute for Virology, Heinrich-Heine-University Düsseldorf
- Since 2012 Full professor (W3) and Director of the Institute of Virology, Medical Center – University of Freiburg
Focus of research
- Experimental virology and immunobiology of cytomegaloviruses (CMV)
- Viral immune evasion strategies
- Clinical virology and vaccines
Selected publications
- Corrales-Aguilar E, Trilling M, Hunold K, FiedlerM, Le VT, Reinhard H, Ehrhardt K, Mercé-Maldonado E, Aliyev E, Zimmermann A, Johnson DC, Hengel H. Human cytomegalovirus Fcγ binding proteins gp34 and gp68 antagonize Fcγ receptors I, II and III. PLoS Pathog. 2014; 10(5):e1004131.
- Stern-Ginossar N, Weisburd B, Michalski A, Le VT, Hein MY, Huang SX, Ma M, Shen B, QianSB, Hengel H, Mann M, Ingolia NT, Weissman JS. Decoding human cytomegalovirus. Science. 2012; 338(6110):1088-93.
- Trilling M, Le VT, Fiedler M, Zimmermann A, Bleifuss E, Hengel H. Identifi cation of DNAdamage DNA-binding protein 1 as a conditional essential factor for cytomegalovirus replication in interferon-γ-stimulated cells. PLoS Pathog. 2011; 7(6):e1002069.
- Zimmermann A, Trilling M, Wagner M, Wilborn M, Bubic I, Jonjic S, Koszinowski U, Hengel H. A cytomegaloviral protein reveals a dual role for STAT2 in IFN-{gamma} signaling and antiviral responses. J Exp Med. 2005; 201(10):1543-53.
- Hengel H, Koopmann JO, Flohr T, Muranyi W, Goulmy E, Hämmerling GJ, Koszinowski UH, Momburg F. A viral ER-resident glycoprotein inactivates the MHC-encoded peptide transporter. Immunity. 1997; 6(5):623-32.
Research methods
- Mouse CMV infection model
- BACmid-based mutagenesis