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Quante

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Prof. Dr.
Michael Quante

Department of Medicine II

Phone: 0049-761-270-32768

www.uniklinik-freiburg.de/itg-en

CV

  • 2006-2008 Clinical Fellow, Medizinische Klinik II, Universität Bonn
  • 2008-2011 Postdoctoral Fellow, Columbia University Medical Center, New York
  • 2011-2019 Max Eder Investigator of the Deutsche Krebshilfe
  • 2011-2020 Clinical Fellow and Consultant Klinik und Poliklinik für Innere Medizin II, Klinikum rechts der Isar, Technical University of Munich
  • Since 2020 Full Professor for Gastrointestinal Oncology, University of Freiburg

Focus of research

  • Barrett Esophagus and Esophageal Adenocarcinma
  • Cancer Prevention ans Surveillance
  • Microenvironment as a stem cell niche

Selected publications

  • Kunze, B., F. Wein, H.Y. Fang, A. Anand, T. Baumeister, J. Strangmann, S. Gerland, J. Ingermann, N.S. Munch, M. Wiethaler, V. Sahm, A.H. Sastre, S. Lange, C.J. Lightdale, A. Bokhari, G.W. Falk, R.A. Friedman, G.G. Ginsberg, P.G. Iyer, Z. Jin, H. Nakagawa, C.J. Shawber, T. Nguyen, W.J. Raab, P. Dalerba, A.K. Rustgi, A.R. Sepulveda, K.K. Wang, R.M. Schmid, T.C. Wang, J.A. Abrams, and M. Quante.
    Notch Signaling Mediates Differentiation in Barrett's Esophagus and Promotes Progression to Adenocarcinoma. Gastroenterology, 2020, Aug;159(2):575-590.
  • Munch, N.S., H.Y. Fang, J. Ingermann, H.C. Maurer, A. Anand, V. Kellner, V. Sahm, M. Wiethaler, T. Baumeister, F. Wein, H. Einwachter, F. Bolze, M. Klingenspor, D. Haller, M. Kavanagh, J. Lysaght, R. Friedman, A.J. Dannenberg, M. Pollak, P.R. Holt, S. Muthupalani, J.G. Fox, M.T. Whary, Y. Lee, T.Y. Ren, R. Elliot, R. Fitzgerald, K. Steiger, R.M. Schmid, T.C. Wang, and M. Quante.
    High-fat Diet Accelerates Carcinogenesis in a Mouse Model of Barrett's Esophagus via IL8 and Alterations to the Gut Microbiome. Gastroenterology, 2019 Aug;157(2):492-506.e2
  • Fang, H.Y., N.S. Munch, M. Schottelius, J. Ingermann, H. Liu, M. Schauer, S. Stangl, G. Multhoff, K. Steiger, C. Gerngross, M. Jesinghaus, W. Weichert, A.A. Kuhl, A.R. Sepulveda, H.J. Wester, T.C. Wang, and M. Quante.
    CXCR4 is a potential target for diagnostic PET/CT imaging in Barrett's dysplasia and esophageal adenocarcinoma. Clin Cancer Res, 2018 Mar 1;24(5):1048-1061.
  • Quante, M., G. Bhagat, J.A. Abrams, F. Marache, P. Good, M.D. Lee, Y. Lee, R. Friedman, S. Asfaha, Z. Dubeykovskaya, U. Mahmood, J.L. Figueiredo, J. Kitajewski, C. Shawber, C.J. Lightdale, A.K. Rustgi, and T.C. Wang.
    Bile acid and inflammation activate gastric cardia stem cells in a mouse model of Barrett-like metaplasia. Cancer Cell, 2012. 21(1): p. 36-51.
  • Quante, M., S.P. Tu, H. Tomita, T. Gonda, S.S. Wang, S. Takashi, G.H. Baik, W. Shibata, B. Diprete, K.S. Betz, R. Friedman, A. Varro, B. Tycko, and T.C. Wang.
    Bone marrow-derived myofibroblasts contribute to the mesenchymal stem cell niche and promote tumor growth. Cancer Cell, 2011. 19(2): p. 257-72.