Pfanner

Prof. Dr.
Nikolaus Pfanner
Institute of Biochemistry and Molecular BiologyDepartment Biochemistry I
Head of Department
Phone: 0049-761-203-5223
nikolaus.pfanner@biochemie.uni-freiburg.de
www.biochemie.uni-freiburg.de/praambel-en?set_language=en
CV
- 1978-1984 Studies of Medicine, University of Munich
- 1985/86 and 1988/89 Postdoctoral/Research fellow in Munich and Princeton (USA)
- 1987-1992 Group Leader at the University of Munich
- Since 1992 Full Professor (C4) and Director of Department Biochemistry I, University of Freiburg
- 2002 Max Planck Research Award
- 2004 Gottfried Wilhelm Leibniz Prize
- 2008 Research Award of the State of Baden-Württemberg
- 2014 Stein & Moore Award (USA)
Focus of research
- Sorting of proteins in cells
- Biogenesis and architecture of cellular powerhouses (mitochondria)
Selected publications
- Harbauer AB, Opalińska M, Gerbeth C, Herman JS, Rao S, Schönfi sch B, Guiard B, Schmidt O, Pfanner N*, Meisinger C*. Cell cycle-dependent regulation of mitochondrial preprotein translocase. Science. 2014; 346(6213):1109-13.
- Chacinska A, Koehler CM, Milenkovic D, Lithgow T, Pfanner N. Importing mitochondrial proteins: machineries and mechanisms. Cell. 2009; 138(4):628-44.
- Kutik S, Stojanovski D, Becker L, Becker T, Meinecke M, Krüger V, Prinz C, Meisinger C, Guiard B, Wagner R, Pfanner N, Wiedemann N. Dissecting membrane insertion of mitochondrial beta-barrel proteins. Cell. 2008; 132(6):1011-24.
- Rehling P, Model K, Brandner K, Kovermann P, Sickmann A, Meyer HE, Kühlbrandt W, Wagner R, Truscott KN, Pfanner N. Protein insertion into the mitochondrial inner membrane by a twin-pore translocase. Science. 2003; 299(5613):1747-51.
- Hill K, Model K, Ryan MT, Dietmeier K, Martin F, Wagner R, Pfanner N. Tom40 forms the hydrophilic channel of the mitochondrial import pore for preproteins. Nature. 1998; 395(6701):516-21.
Research methods
- Cell-free analysis of protein transport
- Characterization of isolated mitochondria