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Eisenhardt

Prof. Dr.
Steffen U. Eisenhardt

Department of Plastic Surgery
Phone: 0049-761-270-25730

www.uniklinik-freiburg.de/plastischechirurgie

CV

  • 1998-2005 Medical Studies, University of Freiburg
  • 2005-2007 Postdoc, Baker Heart and Diabetes Institute, Melbourne, Australia
  • 2008-2014 Residency, Plastics surgery and Hand surgery
  • 2014 Associate Professor and Consultant Plastic Surgeon, Department of Plastic Surgery, Medical Center - University of Freiburg
  • Since 2017 Full Professor (W3- Heisenberg Professorship), Head, Section of Reconstructive Microsurgery

Focus of Research

  • Innate Immunity, Innate Memory
  • Immunology of allotransplant rejection
  • „Liquid biopsy“ and tumormarkers in soft tissue sarcomas

Selected publications

  • Braig D, Nero TL, Koch HG, Kaiser B, Wang X, Thiele JR, Morton CJ, Zeller J, Kiefer J, Potempa LA, Mellett NA, Miles LA, Du XJ, Meikle PJ, Huber-Lang M, Stark GB, Parker MW, Peter K, Eisenhardt SU. Transitional changes in the CRP structure lead to the exposure of proinflammatory binding sites. Nat Commun. 2017; 8:14188.
  • Eisenhardt SU, Weiss JB, Smolka C, Maxeiner J, Pankratz F, Bemtgen X, Kustermann M, Thiele JR, Schmidt Y, Bjoern Stark G, Moser M, Bode C, Grundmann S. MicroRNA-155 aggravates ischemia-reperfusion injury by modulation of inflammatory cell recruitment and the respiratory oxidative burst. Basic Res Cardiol. 2015; 110(3):32.
  • Fricke A, Ullrich PV, Heinz J, Pfeifer D, Scholber J, Herget GW, Hauschild O, Bronsert P, Stark GB, Bannasch H, Eisenhardt SU*, Braig D*. Identification of a blood-borne miRNA signature of synovial sarcoma. Mol Cancer. 2015; 14:151.
  • Thiele JR, Habersberger J, Braig D, Schmidt Y, Goerendt K, Maurer V, Bannasch H, Scheichl A, Woollard KJ, von Dobschütz E, Kolodgie F, Virmani R, Stark GB, Peter K, Eisenhardt SU. Dissociation of pentameric to monomeric C-reactive protein localizes and aggravates inflammation: in vivo proof of a powerful proinflammatory mechanism and a new anti-inflammatory strategy. Circulation. 2014; 130(1):35-50.
  • Eisenhardt SU, Habersberger J, Murphy A, Chen YC, Woollard KJ, Bassler N, Qian H, von Zur Muhlen C, Hagemeyer CE, Ahrens I, Chin-Dusting J, Bobik A, Peter K. Dissociation of pentameric to monomeric C-reactive protein on activated platelets localizes inflammation to atherosclerotic plaques. Circ Res. 2009; 105(2):128-37.

Research methods

  • Intravital Imaging
  • Ex vivo flow-chamber circulation assays
  • Allotransplantation models